How does it work?
The main active ingredient of this preparation is 12% salicylic acid and 4% lactic acid
Salicylic acid belongs to the group of medicines known as keratolytics. Salicylic acid works by breaking down keratin, a protein which forms part of the skin structure. This results in the shedding of skin cells from the affected area.
In the treatment of warts, calluses and verrucas, the effect of salicylic acid is to remove the affected skin over a period of time. If successful, the new skin which grows underneath will be healthy.
|What is it used for?
Salatac Gel should be applied once daily. The gel should be applied once every night. Treatment can take up to twelve (12) weeks for persistent verrucas to disappear, and it is necessary to persevere with treatment.
1. Every night, soak the affected site in warm water for 2 to 3 minutes.
Avoid use on broken or inflamed skin.
Not suitable for use on the face or anogenital areas.
Avoid use of this product on large areas of skin, as this may result in absorption of sufficient quantities to cause adverse effects.
Keep away from naked flames.
Avoid inhaling vapour
Not to be used in
Known sensitivity or allergy to any ingredient
Narrowing of blood vessels in the extremities (peripheral vascular disease)
Not to be used on moles, birthmarks, hairy warts or on any other skin lesions.
Numbness and weakness in the extremities, caused by damage to the nerves (peripheral neuropathy)
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
There are no known harmful effects when this medicine is used during pregnancy.
There are no known harmful effects when this medicine is used by breastfeeding mothers.
Caution flammable: keep medication away from fire or flames.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug’s manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor.
How can this medicine affect other medicines?
There are no known interactions with other medicines.
Overdose or Pain from Use
Any excessive use of Salatac Gel could cause irritation of the skin. If this occurs, Salatac Gel should be used more sparingly or applied less frequently. If in any doubt visit your health professional for advice.
Pharmacodynamic properties: The active ingredients, salicylic acid and lactic acid, are well-established pharmacopoeial substances. In combination, they are routinely used in the treatment of verrucas, warts, corns and calluses for their keratolytic properties.
When applied topically, and in high enough concentrations, salicylic acid acts by achieving a slow, painless destruction of the thickened stratum corneum. It softens and destroys the stratum corneum of the affected tissue by reducing the adhesiveness of the corneocytes while causing the cornified epithelium to swell, soften, macerate and finally desquamate. In the treatment of warts, a mild irritant reaction, which may render the virus more prone to immunologic stimulation or response, may add to the mechanical removal of infected cells. The other active ingredient, lactic acid, enhances the availability of the salicylic acid from the dried collodion, in addition to having antiseptic and caustic properties.
Pharmacokinetic properties: Salatac Gel contains 12% salicylic acid and 4% lactic acid in an evaporative collodion-like gel which forms a cohesive and adhesive film on the skin.
The formulation is presented in a collapsible aluminium tube fitted with a special applicator nozzle allowing the formulation to be dispensed precisely to the affected areas only. This minimises the spread of the preparation onto the surrounding healthy skin.
The gel quickly forms a surface film, well before it dries completely, thereby prolonging the period during which the keratolytic solution can properly infiltrate and achieve intimate contact with the surface layer of the thickened stratum corneum.
Furthermore, even when the film appears to have dried completely, the inclusion of the non-evaporative lactic acid ensures that a proportion of the salicylic acid remains in solution within the vehicle, thus permitting continued release of the keratolytic, which may otherwise be entrapped within the collodion-like film.
Systemic absorption of salicylic acid or lactic acid after application of the recommended daily dose of one or two drops of the preparation to small, circumscribed areas is exceedingly unlikely.